Product Overview

PT‑141, also known as Bremelanotide, is a synthetic melanocortin receptor agonist peptide studied in research settings for its ability to interact with specific melanocortin receptors. It is derived from the peptide melanotan II but differs in its receptor affinity profile.

In scientific research, PT‑141 is investigated for its effects on neuroendocrine signaling and receptor engagement in cellular and animal models. It is supplied as a research‑grade peptide suitable for experimental studies and laboratory applications — not for clinical or therapeutic use.

Mechanism of Action (Research Context)

PT‑141 functions as an agonist for melanocortin receptors, particularly MC3R and MC4R, which are involved in various physiological signaling processes. In controlled experimental settings, activation of these receptors has been associated with modulation of neural circuitry related to sexual response pathways, thermoregulation, and energy homeostasis.

Because it acts centrally on melanocortin receptors, PT‑141 is used in endocrine and neural signaling studies to explore receptor interaction, peptide signaling effects, and downstream physiological pathways in laboratory models.

Key Features & Scientific Highlights

📌 Melanocortin Receptor Agonist: PT‑141 engages melanocortin receptors (especially MC3R and MC4R) in experimental systems.

📌 Research Focus: Often used as a tool compound in studies examining melanocortin signaling pathways, neuroendocrine function, and receptor pharmacology.

📌 High‑Purity Peptide: Supplied as a lyophilized white powder for controlled laboratory experiments.

📌 Derived from Melanocortin Family: Structurally related to melanocortin peptides such as Melanotan II, but with distinct receptor activity profiles studied in research.

Research Applications

Researchers employ PT‑141 in scientific and experimental investigations to explore:

• Melanocortin receptor signaling and pharmacology — understanding how activation of MC receptors affects cell signaling pathways.
• Neuroendocrine and neural pathways — examining peptide‑mediated neural communication and physiological responses in lab models.
• Receptor binding dynamics — studying how receptors interact with peptide ligands and downstream effects.
• Mechanistic peptide research — testing hypotheses related to melanocortin receptor engagement and subsequent intracellular pathways.

These applications help scientists better understand how specific peptide modulators interact with receptors and influence complex signaling networks in biological systems.

Chemical & Biological Profile

• Common Name: PT‑141
• Other Name: Bremelanotide
• Peptide Class: Melanocortin receptor agonist
• Receptor Targets: MC3R, MC4R (studied in research models)
• Form: Lyophilized white powder for research experiments

Usage & Safety Notice

✅ This product is intended strictly for research and laboratory use only.
❗ It is not intended for human or veterinary therapeutic use, clinical treatment, or ingestion.
⚠️ Always follow proper laboratory procedures, peptide handling protocols, and appropriate safety guidelines when working with this compound.